A serene lake with trees reflecting in the water, surrounded by a forest of tall, slender trees with autumn foliage.

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Top Cities in Orangeburg County

A calm lake with autumn-colored trees and a clear blue sky.
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Orangeburg

Orangeburg

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Sep 18 - Sep 20
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Sep 25 - Sep 27

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Our top choices for Orangeburg County hotels

A patio area with wicker furniture, a stone fire pit, and outdoor seating.

1. Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,004 reviews)
"Property was clean and the breakfast was delicious would stay there again."
United States
Melissa
$134 nightly
The price is $149
Sep 20 - Sep 21
Total with taxes and fees
Fairfield Inn & Suites by Marriott Santee
A hotel room with two beds, a grey armchair, a nightstand with a phone, and a cityscape picture on the wall.

2. Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,489 reviews)
"Very quiet, dog friendly, clean, breakfast included."
United States
Yomerys
$80 nightly
The price is $89
Sep 13 - Sep 14
Total with taxes and fees
Baymont by Wyndham Santee
A breakfast area with a self-service counter, refrigerated display, and a digital menu board.

3. Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (953 reviews)
"Great place to stay!"
United States
Connor
$98 nightly
The price is $108
Sep 20 - Sep 21
Total with taxes and fees
Tru By Hilton Santee
A modern indoor pool area with a table and chairs, large windows, and a poolside lounge with sun loungers.

4. Spark by Hilton Orangeburg

Spark by Hilton Orangeburg
2.5 star property
Orangeburg
7.8 out of 10, Good, (1,001 reviews)
"My stay was comfortable and awesome I will be visiting again"
United States
TaNikka
$98 nightly
The price is $108
Sep 15 - Sep 16
Total with taxes and fees
Spark by Hilton Orangeburg
A self-service kiosk with a beverage cooler, microwave, and various food items.

5. Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1,001 reviews)
"great hotel"
Canada
Andrew
$114 nightly
The price is $127
Sep 27 - Sep 28
Total with taxes and fees
Tru by Hilton Orangeburg
A hotel entrance with a sign reading "Best Western PLISS."

6. Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,000 reviews)
"Breakfast was good, staff very helpful."
United States
Bonnie
$111 nightly
The price is $123
Sep 20 - Sep 21
Total with taxes and fees
Best Western Plus Santee Inn
A water park with a pool, slides, and umbrellas.

7. Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very Good, (1,003 reviews)
"I stay here all the time when traveling with my dog. This place is super clean and the staff is excellent."
United States
Dennis
$106 nightly
The price is $118
Sep 27 - Sep 28
Total with taxes and fees
Holiday Inn Santee by IHG
A hotel room with a large bed, a desk, a chair, a desk lamp, and a wall-mounted lamp.

8. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,001 reviews)
"Was a good place to stay"
United States
santa
$103 nightly
The price is $115
Oct 4 - Oct 5
Total with taxes and fees
Comfort Inn & Suites Santee
A tent with a view of a lake and boats, a wooden chair, and a potted plant.

9. Bells Marina & Resort

Bells Marina & Resort
2.5 star property
Eutawville
8.6 out of 10, Excellent, (99 reviews)
"If you’re looking for a quiet and peaceful getaway this place was great! The lake is beautiful and you can kayak or just sit out by the water and relax. The cute ducks in the property were my favorite. Would definitely go back again."
United States
Amber
$76 nightly
The price is $84
Sep 21 - Sep 22
Total with taxes and fees
Bells Marina & Resort
A hotel dining area with multiple tables and chairs, a large flat-screen TV, and a patterned wall design.

10. Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,001 reviews)
"I’ve stayed there many times before always happy with it ."
United States
Janice
$125 nightly
The price is $139
Sep 27 - Sep 28
Total with taxes and fees
Hampton Inn Santee-I-95
A breakfast bar with pastries, fruits, and a vase with flowers.

11. Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg
2.0 star property
Orangeburg
8.2 out of 10, Very Good, (1,001 reviews)
"The place was nice and clean"
United States
Arsenio
$75 nightly
The price is $83
Oct 6 - Oct 7
Total with taxes and fees
Travelodge by Wyndham Orangeburg
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

12. Quality Inn & Suites Orangeburg

Quality Inn & Suites Orangeburg
2.5 star property
Orangeburg
6.2 out of 10, (702 reviews)
"I like everything."
United States
Ruben
$60 nightly
The price is $66
Oct 4 - Oct 5
Total with taxes and fees
Quality Inn & Suites Orangeburg
A lobby with a reception desk, a sofa, a small round table, and an American flag.

13. Holiday Inn Express & Suites Orangeburg by IHG

Holiday Inn Express & Suites Orangeburg by IHG
2.5 star property
Orangeburg
8.6 out of 10, Excellent, (854 reviews)
"Helpful staff, great breakfast buffet"
United States
Jenelyn
$103 nightly
The price is $114
Oct 11 - Oct 12
Total with taxes and fees
Holiday Inn Express & Suites Orangeburg by IHG
A modern kitchen with dark cabinets, a granite countertop, a ceiling fan, a flat-screen TV, and a breakfast bar with pastries.

14. Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (588 reviews)
"Rooms are clean and staff was super nice and accommodating "
United States
Will
$63 nightly
The price is $69
Sep 20 - Sep 21
Total with taxes and fees
Quality Inn & Suites Santee I-95
A stone fireplace with a television mounted above it, a small statue on the mantel, and a wooden cabinet to the left.

15. Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
3.0 star property
Orangeburg
8.4 out of 10, Very Good, (825 reviews)
"Amazing hotel. Always my go to whenever I am staying in Orangeburg. Highly recommended!"
United States
Percy
$105 nightly
The price is $117
Sep 17 - Sep 18
Total with taxes and fees
Fairfield Inn by Marriott Orangeburg
A spacious dining area with multiple tables and chairs, a reception desk, and large windows providing natural light.

16. SpringHill Suites by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg
2.5 star property
Orangeburg
8.8 out of 10, Excellent, (814 reviews)
"Great Place to Stay!"
United States
Henrietta
$109 nightly
The price is $121
Sep 20 - Sep 21
Total with taxes and fees
SpringHill Suites by Marriott Orangeburg

17. Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
2.0 star property
Santee
6.4 out of 10, (591 reviews)
"The price rate was great"
United States
Stevenson
$71 nightly
The price is $79
Sep 27 - Sep 28
Total with taxes and fees
Ramada by Wyndham Santee I-95
A Hampton Inn & Suites hotel with a modern design, featuring a parking lot and a well-lit entrance.

18. Hampton Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg
2.5 star property
Orangeburg
9.4 out of 10, Exceptional, (842 reviews)
"Everything about the hotel was great"
United States
RODERICK V
$130 nightly
The price is $145
Sep 27 - Sep 28
Total with taxes and fees
Hampton Inn & Suites Orangeburg
A hotel room with a bed, a desk, a chair, a sofa, and a table.

19. Baymont by Wyndham Orangeburg North

Baymont by Wyndham Orangeburg North
2.5 star property
Orangeburg
5.8 out of 10, (1,001 reviews)
"Everything was fine."
United States
SHERRY
$55 nightly
The price is $61
Sep 27 - Sep 28
Total with taxes and fees
Baymont by Wyndham Orangeburg North
A hotel room with two beds, a desk, a mirror, and a wall-mounted TV.

20. Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (773 reviews)
"The staff was very helpful and respectful."
United States
Mark
$64 nightly
The price is $71
Sep 15 - Sep 16
Total with taxes and fees
Travelodge by Wyndham Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Great weekend hotel deals in Orangeburg County, SC

Showing deals for:Sep 25 - Sep 27

Image gallery for The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot.

Property grounds

The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot.

Eutawville
10/10Exceptional (42 reviews)
6% off
$153 nightly
Price is $493
Total with taxes and fees
The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot.
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Top Orangeburg County Hotel Reviews

Tru by Hilton Orangeburg

Tru by Hilton Orangeburg

10/10 Excellent
"Good stay"
Anthony 3-night trip
Posted 8 hours ago
Tru by Hilton Orangeburg

Price trends for hotels in Orangeburg County

Less expensive
More expensive
This month
Next month
May
June
$98
$93
Month
Price
January
$87
February
$96
March
$91
April
$93
May
$66
June
$109
July
$108
August
$94
September
$98
October
$93
November
$91
December
$85
Price trend information excludes taxes and fees and is based on base rates for a nightly stay for 2 adults found in the last 7 days on our site and averaged for commonly viewed hotels in Orangeburg County. Select dates and complete search for nightly totals inclusive of taxes and fees.

Frequently asked questions

How much do hotels in Orangeburg County cost?
Prices for Orangeburg County hotels vary depending on the season and other factors, like Easter and school holidays. You can find cheap options from $61 in a few different ways. Enter your destination and travel dates and then pick your budget using the "Price per night" filter. You can then refine your search by choosing your preferred amenities and more.
When is the best time to go to Orangeburg County?
That all depends on what you want from your trip to Orangeburg County. If you want to visit in summer, which is between June and August, expect average temperatures of between 72ºF and 90ºF. Orangeburg County has a humid subtropical climate, so keep that in mind when packing.
How can I find cheap hotels in Orangeburg County?
The best place to begin your search is with our "Price per night" filter. At the moment, the cheapest properties start at $61 per night. Other ways to grab a budget-friendly Orangeburg County escape are by booking as early as possible and being flexible with the dates you travel. For even more great deals, go to our cheap hotels in Orangeburg County page.
What are the best hotels in Orangeburg County for families?
Pack your bags (and the little ones!) and prepare for an action-packed vacation at one of our top family-friendly hotels in Orangeburg County. Located in Santee, Fairfield Inn & Suites by Marriott Santee is a fabulous pick. Complimentary breakfast and a firepit are among the amenities here. Or kick back with the fam at Hampton Inn Santee-I-95. You can also find your ideal stay by clicking on the "Family friendly" box in the "Traveler experience" section of our handy filters.
Why should I book my Orangeburg County hotel with Expedia?
Book an Orangeburg County hotel with Expedia for choice, price and ease. Also, our One Key™ rewards program lets you earn OneKeyCash™* on eligible hotels, vacation rentals, flights, car rentals and more. In addition, we offer flexibility in case your itinerary changes, and if you want to ask us anything or need assistance, our online Help Center is always available. *OneKeyCash disclaimer - OneKeyCash is not redeemable for cash and can only be used on Hotels.com, Expedia and Vrbo.

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