Search Hotels in Orangeburg County

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Compare 588 hotels in Orangeburg County with room rates, reviews, and availability. Most hotels are fully refundable.

Baymont by Wyndham Santee

2.5 star property
8.0 out of 10, Very Good, (1345)
"A nice location, plenty of parking, nice that breakfast was included. "
$75 nightly
The price is $83
Oct 5 - Oct 6
Total with taxes and fees
Baymont by Wyndham Santee

Tru by Hilton Orangeburg

2.5 star property
9.2 out of 10, Wonderful, (1000)
"Great little hotel. Perfect for a short stay. "
$122 nightly
The price is $136
Oct 20 - Oct 21
Total with taxes and fees
Tru by Hilton Orangeburg

Tru By Hilton Santee

2.5 star property
9.2 out of 10, Wonderful, (552)
"Great stay"
$110 nightly
The price is $122
Oct 12 - Oct 13
Total with taxes and fees
Tru By Hilton Santee

Spark by Hilton Orangeburg

2.5 star property
7.8 out of 10, Good, (1003)
"Very close to highway, I come to the area 3 times a year, and this is the nicest place yet"
$87 nightly
The price is $97
Oct 12 - Oct 13
Total with taxes and fees
Spark by Hilton Orangeburg

Fairfield Inn & Suites by Marriott Santee

2.5 star property
9.8 out of 10, Exceptional, (1000)
"Great stay for a quick weekend getaway!"
$134 nightly
The price is $149
Oct 5 - Oct 6
Total with taxes and fees
Fairfield Inn & Suites by Marriott Santee

Quality Inn & Suites

2.5 star property
6.0 out of 10, (440)
"The rooms are old but very clean and spacious. Only downfall is a loud machinery noise nearby. Not sure of the source. "
$64 nightly
The price is $71
Oct 12 - Oct 13
Total with taxes and fees
Quality Inn & Suites

Holiday Inn Santee by IHG

3.0 star property
8.2 out of 10, Very Good, (950)
"Nice clean, great location "
$118 nightly
The price is $131
Nov 2 - Nov 3
Total with taxes and fees
Holiday Inn Santee by IHG

Days Inn by Wyndham Orangeburg

2.0 star property
5.6 out of 10, (694)
"Simple hotel "
$48 nightly
The price is $54
Oct 12 - Oct 13
Total with taxes and fees
Days Inn by Wyndham Orangeburg

Fairfield Inn by Marriott Orangeburg

2.5 star property
8.4 out of 10, Very Good, (648)
"Staff were very friendly, room was nice and clean and the hot breakfast was amazing!"
$84 nightly
The price is $93
Oct 5 - Oct 6
Total with taxes and fees
Fairfield Inn by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg

2.5 star property
9.0 out of 10, Wonderful, (647)
"It was very nice hotel "
$109 nightly
The price is $121
Oct 13 - Oct 14
Total with taxes and fees
SpringHill Suites by Marriott Orangeburg

Hampton Inn Santee-I-95

2.5 star property
9.6 out of 10, Exceptional, (1000)
"Staff was very friendly and accommodating. "
$135 nightly
The price is $149
Nov 2 - Nov 3
Total with taxes and fees
Hampton Inn Santee-I-95

Comfort Inn & Suites Santee

2.5 star property
8.0 out of 10, Very Good, (1000)
"Great place to stay."
$105 nightly
The price is $117
Oct 12 - Oct 13
Total with taxes and fees
Comfort Inn & Suites Santee

Travelodge by Wyndham Orangeburg

2.0 star property
8.2 out of 10, Very Good, (1000)
"Clean room, comfortable bed, staff was welcoming "
$89 nightly
The price is $99
Oct 5 - Oct 6
Total with taxes and fees
Travelodge by Wyndham Orangeburg

Holiday Inn Express & Suites Orangeburg by IHG

2.5 star property
8.6 out of 10, Excellent, (781)
"Friendly staff, quiet "
$114 nightly
The price is $127
Oct 26 - Oct 27
Total with taxes and fees
Holiday Inn Express & Suites Orangeburg by IHG

Super 8 by Wyndham, Orangeburg

2.0 star property
6.8 out of 10, (859)
"Glad we had ground floor room."
$58 nightly
The price is $64
Oct 5 - Oct 6
Total with taxes and fees
Super 8 by Wyndham, Orangeburg

Best Western Plus Santee Inn

2.5 star property
8.8 out of 10, Excellent, (1000)
"We really enjoyed our stay and will be back!"
$117 nightly
The price is $130
Oct 12 - Oct 13
Total with taxes and fees
Best Western Plus Santee Inn

Hampton Inn & Suites Orangeburg

2.5 star property
9.4 out of 10, Exceptional, (736)
"Bed was comfortable and the front desk staff wonderful "
$136 nightly
The price is $151
Oct 26 - Oct 27
Total with taxes and fees
Hampton Inn & Suites Orangeburg

Comfort Inn & Suites

2.5 star property
8.0 out of 10, Very Good, (510)
"I was satisfied with staff service and facilities."
$98 nightly
The price is $109
Oct 12 - Oct 13
Total with taxes and fees
Comfort Inn & Suites

Baymont by Wyndham Orangeburg North

2.5 star property
6.0 out of 10, (1003)
"Very clean and quiet "
$69 nightly
The price is $77
Oct 26 - Oct 27
Total with taxes and fees
Baymont by Wyndham Orangeburg North

Travelodge by Wyndham Santee

2.0 star property
7.0 out of 10, Good, (658)
"Good location "
$62 nightly
The price is $69
Oct 5 - Oct 6
Total with taxes and fees
Travelodge by Wyndham Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Orangeburg County Hotel Reviews

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Frequently asked questions

How much do hotels in Orangeburg County cost?
Prices for Orangeburg County hotels vary depending on the season and other factors, like Easter and school holidays. You can find cheap options from $54 in a few different ways. Enter your destination and travel dates and then pick your budget using the "Price per night" filter. You can then refine your search by choosing your preferred amenities and more.
When is the best time to go to Orangeburg County?
That all depends on what you want from your trip to Orangeburg County. If you want to visit in summer, which is between June and August, expect average temperatures of between 72ºF and 90ºF. Orangeburg County has a humid subtropical climate, so keep that in mind when packing.
How can I find cheap hotels in Orangeburg County?
The best place to begin your search is with our "Price per night" filter. At the moment, the cheapest properties start at $54 per night. Other ways to grab a budget-friendly Orangeburg County escape are by booking as early as possible and being flexible with the dates you travel. For even more great deals, go to our cheap hotels in Orangeburg County page.
What are the best hotels in Orangeburg County for families?
Pack your bags (and the little ones!) and prepare for an action-packed vacation at one of our top family-friendly hotels in Orangeburg County. Located in Santee, Fairfield Inn & Suites by Marriott Santee is a fabulous pick. Complimentary breakfast and a firepit are among the amenities here. Or kick back with the fam at Hampton Inn Santee-I-95. You can also find your ideal stay by clicking on the "Family friendly" box in the "Traveler experience" section of our handy filters.
Why should I book my Orangeburg County hotel with Expedia?
Book an Orangeburg County hotel with Expedia for choice, price and ease. Also, our One Key™ rewards program lets you earn OneKeyCash™* on eligible hotels, vacation rentals, flights, car rentals and more. In addition, we offer flexibility in case your itinerary changes, and if you want to ask us anything or need assistance, our online Help Center is always available. *OneKeyCash disclaimer - OneKeyCash is not redeemable for cash and can only be used on Hotels.com, Expedia and Vrbo.